Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of rat ganglionic eminences and cerebral cortex at embryonic stages E12.5, E14 and E16


ABSTRACT: Gene expression profiling of the medial (MGE), lateral (LGE) and caudal (CGE) ganglionic eminence, and cerebral cortex (CTX) at various embryonic stages (E12.5, E14 and E16).

ORGANISM(S): Rattus norvegicus

SUBMITTER: Ruth Luthi-Carter 

PROVIDER: E-MEXP-570 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Comprehensive spatiotemporal transcriptomic analyses of the ganglionic eminences demonstrate the uniqueness of its caudal subdivision.

Willi-Monnerat Susan S   Migliavacca Eugenia E   Surdez Didier D   Delorenzi Mauro M   Luthi-Carter Ruth R   Terskikh Alexey V AV  

Molecular and cellular neurosciences 20080126 4


The elucidation of mechanisms underlying telencephalic neural development has been limited by the lack of knowledge regarding the molecular and cellular aspects of the ganglionic eminence (GE), an embryonic structure that supplies the brain with diverse sets of GABAergic neurons. Here, we report a comprehensive transcriptomic analysis of this structure including its medial (MGE), lateral (LGE) and caudal (CGE) subdivisions and its temporal dynamics in 12.5 to 16 day-old rat embryos. Surprisingly  ...[more]

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