Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of Ralstonia solanacearum hrpB mutant overexpressing hrpG vs wild type strain


ABSTRACT: 1. Comparison of transcripts during growth in pure culture of a wild-type strain compared to a mutant deficient in the transcriptional activator encoded by the gene hrpG.

2. Transcriptome analysis for identification of the hrpG regulon by comparison of a rppG mutant to the wild type strain.

3. Transcriptome analysis comparing a hrpB mutant overexpressing hrpG to the wild type strain.

ORGANISM(S): Ralstonia solanacearum

SUBMITTER: Marc Valls 

PROVIDER: E-MEXP-579 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Integrated regulation of the type III secretion system and other virulence determinants in Ralstonia solanacearum.

Valls Marc M   Genin Stéphane S   Boucher Christian C  

PLoS pathogens 20060801 8


In many plant and animal bacterial pathogens, the Type III secretion system (TTSS) that directly translocates effector proteins into the eukaryotic host cells is essential for the development of disease. In all species studied, the transcription of the TTSS and most of its effector substrates is tightly regulated by a succession of consecutively activated regulators. However, the whole genetic programme driven by these regulatory cascades is still unknown, especially in bacterial plant pathogens  ...[more]

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