Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling of yeast grown in fermentors at different dilution rates

ABSTRACT: the protrotophic laboratory strain CEN.PK113-7D (MAT a) was grown in laboratory fermentors with a working volume of 1 litre at dilution rates of 0.02, 0.05, 0.10 (in triplicate), 0.20 (in triplicate), 0.25, and 0.33 per hour (in triplicate). At steady state, samples from each of the 12 continuous cultures were taken and cooled below 2 degree C within ten seconds by mixing 50\% sample and 50\% crushed ice.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: birgitte regenberg

PROVIDER: E-MEXP-593 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae.

Regenberg Birgitte B Grotkjaer Thomas T Winther Ole O Fausbøll Anders A Akesson Mats M Bro Christoffer C Hansen Lars Kai LK Brunak Søren S Nielsen Jens J Nielsen Jens J

Genome biology 20060101 11

<h4>Background</h4>Growth rate is central to the development of cells in all organisms. However, little is known about the impact of changing growth rates. We used continuous cultures to control growth rate and studied the transcriptional program of the model eukaryote Saccharomyces cerevisiae, with generation times varying between 2 and 35 hours.<h4>Results</h4>A total of 5930 transcripts were identified at the different growth rates studied. Consensus clustering of these revealed that half of ...[more]

PMID: 17105650

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Dataset Information

Transcription profiling of yeast grown in fermentors at different dilution rates

Publications

Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae.

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