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Transcription profiling of DREB2A knock out vs wild type Arabidopsis plants under conditions of drought or high temperature stress

ABSTRACT: DREB2A is a transcription factor responsive to drought, high salt and high temperature stress.In this experiment, gene expression profiles of DREB2A KO mutants were compared with wild type under stress condition.

INSTRUMENT(S): G2565BA DNA microarray scanner [Agilent]

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Kyonoshin Maruyama 

PROVIDER: E-MEXP-603 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Dual function of an Arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expression.

Sakuma Yoh Y   Maruyama Kyonoshin K   Qin Feng F   Osakabe Yuriko Y   Shinozaki Kazuo K   Yamaguchi-Shinozaki Kazuko K  

Proceedings of the National Academy of Sciences of the United States of America 20061009 49

Transcription factor DREB2A interacts with a cis-acting dehydration-responsive element (DRE) sequence and activates expression of downstream genes involved in drought- and salt-stress response in Arabidopsis thaliana. Intact DREB2A expression does not activate downstream genes under normal growth conditions. A negative regulatory domain exists in the central region of DREB2A, and deletion of this region transforms DREB2A to a constitutive active form (DREB2A CA). We carried out microarray analys  ...[more]

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