Transcription profiling of liver from wild type mice of different ages to determine whether gene expression changes in naturally aged mice overlap with those from DNA repair deficient mice

ABSTRACT: To investigate whether and to which extent the gene expression changes in DNA repair deficient mice (i.e. Csbm/m/Xpa-/- and Ercc1-/-) overlap with those observed in a natural aged liver, we sought to compare the full mouse liver transcriptome of adult 16-, 96- and 130-week old wt C57Bl/6J mice (n=4) with that of adult 8-week old wt C57Bl/6J mice

ORGANISM(S): Mus musculus

SUBMITTER: Gijsbertus van der Horst 

PROVIDER: E-MEXP-839 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress