Transcription profiling of rodent hepatic carcinogenesis

ABSTRACT: 3 dose levels of each of 9 compounds were used to dose male SD rats q.d. by oral gavage. Compounds included 5 nongenotoxic carcinogens (bemitradine, clofibrate, doxylamine, methapyrilene, & phenobarbital), 2 genotoxic agents (tamoxifen and 2-AAF) and 2 non-carcinogens (4-AAF and isoniazid). This work has been described in Kramer JA, Curtiss SW, Kolaja KL, Alden CA, Blomme EAG, Curtiss WC, Davila JC, Jackson CJ, and Bunch RT. (2004) Acute Molecular Markers of Rodent Hepatic Carcinogenesis Identified by Transcription Profiling. Chem. Res. Toxicol., in press.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Jeffrey Kramer 

PROVIDER: E-MEXP-89 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress