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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human duodenal mucosa from healthy volunteers perfused with 0.055 M glutamine (10 ml/min) in saline at 10 cm distally from the pylorus for 4 h or continuous injection of 0.055 M glucose in saline

ABSTRACT: Intestinal perfusion of a 40-cm segment of the small intestine in 8 healthy volunteers. 2 test days, overnight fast. Gastroduodenoscopy for tissue sampling and positioning of perfusion catheter. Continuous injection of 0.055 M glutamine (10 ml/min) in saline at 10 cm distally from the pylorus for 4 h or continuous injection of 0.055 M glucose in saline. After the injection a second gastroduodenoscopy takes place for tissue sampling. In total we have 4 samples per individual (placebo-before; placebo-after; glutamine-before; and glutamine-after injection.

INSTRUMENT(S): HP GeneArray [Affymetrix/HP]

ORGANISM(S): Homo sapiens

SUBMITTER: Rachel van Haaften

PROVIDER: E-MEXP-941 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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