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Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of microdissected human microdissected pancreas ductal adenocarcinoma vs. microdissected normal duct cells

ABSTRACT: Comparison of the gene expression of microdissected pancreas ductal adenocarcinoma to microdissected normal duct cells

ORGANISM(S): Homo sapiens

SUBMITTER: Christian Pilarsky

PROVIDER: E-MEXP-950 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays.

Grützmann Robert R Pilarsky Christian C Ammerpohl Ole O Lüttges Jutta J Böhme Armin A Sipos Bence B Foerder Melanie M Alldinger Ingo I Jahnke Beatrix B Schackert Hans Konrad HK Kalthoff Holger H Kremer Bernd B Klöppel Günter G Saeger Hans Detlev HD

Neoplasia (New York, N.Y.) 20040901 5

Pancreatic ductal adenocarcinoma (PDAC) remains an important cause of malignancy-related death and is the eighth most common cancer with the lowest overall 5-year relative survival rate. To identify new molecular markers and candidates for new therapeutic regimens, we investigated the gene expression profile of microdissected cells from 11 normal pancreatic ducts, 14 samples of PDAC, and 4 well-characterized pancreatic cancer cell lines using the Affymetrix U133 GeneChip set. RNA was extracted f ...[more]

PMID: 15548371

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