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Transcription profiling of human benign and malignant thyroid follicular neoplasi

ABSTRACT: Differentiation between Follicular Thyroid Carcinoma and Follicular Thyroid Adenoma based on their genetic signature

ORGANISM(S): Homo sapiens

DISEASE(S): follicular thyroid carcinoma

SUBMITTER: Micheala Aldred

PROVIDER: E-MEXP-97 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genetic classification of benign and malignant thyroid follicular neoplasia based on a three-gene combination.

Weber Frank F Shen Lei L Aldred Micheala A MA Morrison Carl D CD Frilling Andrea A Saji Motoyasu M Schuppert Frank F Broelsch Christoph E CE Ringel Matthew D MD Eng Charis C

The Journal of clinical endocrinology and metabolism 20050215 5

Thyroid carcinoma is a common endocrine cancer with a favorable prognosis if subjected to timely treatment. However, the clinical identification of follicular thyroid carcinoma (FTC) among patients with benign thyroid nodules is still a challenge. Preoperative fine needle aspiration-based cytology cannot always differentiate follicular carcinomas from benign follicular neoplasias. Because current methods fail to improve preoperative diagnosis of thyroid nodules, new molecular-based diagnoses sho ...[more]

PMID: 15713710

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Transcription profiling of human thyroid follicular adenomas and thyroid papillary carcinomas to discriminate benign and malignant tumors

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