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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Single cell RNA sequencing of naive and primed human pluripotent stem cells treated with SB431542

ABSTRACT: The aim of this experiment was to investigate the role of TGFβ signalling in human pluripotency, looking at the effect of SB431542 (SB), a potent and selective SMAD inhibitor that blocks TGFβ/Activin receptors ALK5, ALK4, and ALK7, on gene expression. We performed 10X sequencing in naïve and primed human pluripotent stem cells (hPSCs) during a time-course of SB treatment.

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Homo sapiens

SUBMITTER: Anna Osnato

PROVIDER: E-MTAB-10018 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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