Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Single-cell RNA-seq of rat microglia in monoculture and in coculture with neurons and astrocytes


ABSTRACT: Microglia, brain resident macrophages, require instruction from the central nervous system microenvironment to maintain their identity, morphology, and to regulate inflammatory responses. We investigated the heterogeneity of response of microglia to the presence of neurons and astrocytes by performing single-cell sequencing of microglia in both monoculture, and in coculture with neurons and astrocytes.

INSTRUMENT(S): NextSeq 550

ORGANISM(S): Rattus norvegicus

SUBMITTER: Owen Robert Dando 

PROVIDER: E-MTAB-10030 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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