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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Single Cell Multi-Omics of Human Preimplantation Embryos Demonstrates Susceptibility to Excess Glucocorticoid Exposure (small RNA part)

ABSTRACT: We then utilized parallel single-cell RNA sequencing and bisulfite sequencing to explore the impact of GC exposure on the human embryo. In addition, to further explore the role of epigenetic regulation as a mechanism for the observed transcriptional changes, we examined the effects of GCs on small non-coding RNA using smallseq.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Homo sapiens

SUBMITTER: Cheng Zhao

PROVIDER: E-MTAB-10098 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Single Cell Multi-Omics of Human Preimplantation Embryos Demonstrates Susceptibility to Excess Glucocorticoid Exposure

Project description:We then utilized parallel single-cell RNA sequencing and bisulfite sequencing to explore the impact of GC exposure on the human embryo. In addition, to further explore the role of epigenetic regulation as a mechanism for the observed transcriptional changes, we examined the effects of GCs on small non-coding RNA using smallseq.

2022-08-02 | E-MTAB-10096 | biostudies-arrayexpress

Single Cell Multi-Omics of Human Preimplantation Embryos Demonstrates Susceptibility to Excess Glucocorticoid Exposure(BSseq part)

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Single-cell RNA-seq reveal lineage formation and X-chromosome dosage compensation in human preimplantation embryos

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array-CGH on single blastomeres from day-4 human preimplantation fresh and frozen embryos

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