Project description:Candida albicans lab strain SC5314 was daily passaged in YPD broth supplemented with fluconazole. Some fluconazole-resistant and some fluconazole-tolerant adaptors were sequenced.
Project description:Lodderomyces elongisporus strain LE750 was exposed to a combination of Hsp90 inhibitor or calcineurin inhibitor+fluconazole. Four resistant mutants were sequenced.
Project description:Lodderomyces elongisporus strain LE750 was exposed to high amount of fluconazole. Five tolerant mutants, as well as the parent, were sequenced.
Project description:Candida albicans lab strain SC53114 was used to obtain fluconazole-tolerant adaptors. 53 adaptors as well as the parent strain were sequenced.
Project description:Candida albicans isolate YJB-T490 was spread on YPD plates supplemented with fluconazole. The plates were incubated at 37C. 54 adaptors were sequenced.
Project description:Candida haemulonii wild type strain TJ180 were expsoured to 64 and 128 μg/ml fluconazole. 14 resistant mutants as well as the parent were sequenced.
Project description:Candida auris clade III isolate B12039 was spread on YPD plate supplemented with 64 µg/ml fluconazole. Randomly 45 adaptors were chosen for further analysis. We did sequencing of them as as well as the parent.
Project description:Candida auris clade III isolate B12039 was spread on YPD plate supplemented with 128 µg/ml fluconazole. Randomly 39 adaptors were chosen for further analysis. We did sequencing of them as as well as the parent.
Project description:Candida albicans lab strain SC5314 was spread on YPD plates supplemented with echinocandins (caspofungin, anidulafungin, micafungin, rezafungin). The adaptors were tested for tolrance to fluconazole. Randomly 43 tolerant adaptors, as well as the parent SC5314, were sequenced.