RNA-seq of early pregnant (GD6.5) or non-pregnant uterine arteries from stroke-prone spontaneously hypertensive (SHRSP) and wistar kyoto (WKY) rats

ABSTRACT: Chronic hypertension during pregnancy affects both mother and infant but its pathological mechanisms are unclear. Due to ethical limitations human data is available in term tissue only- so deeper understanding of the vascular changes during early pregnancy are unknown. This study utilises a known rat model of chronic hypertension to study changes in gene expression at an early gestational time point. After 6 days of pregnancy animals were sacrificed and main uterine arteries harvested for RNA-Seq (or age-matched virgin rats as controls).

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Rattus norvegicus

SUBMITTER: Kayley Scott 

PROVIDER: E-MTAB-10212 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress