SHP-1 dependent dephosphorylation of Histone H2B acts as a molecular switch to facilitate transcription

ABSTRACT: 1.Comparison of chromatin occupancy of H2BUb and RNA Polymerase II in SHP-1 WT and KO MCF7 cells. Paired end sequencing (2X100 bp) was performed on the Illumina HiSeq X ten. 2.Identification of the SHP-1 binding site in MCF7 cells using ChIP Seq. Paired end sequencing (2X100 bp) was performed on the Illumina Nextseq 2000 platform.

INSTRUMENT(S): NextSeq 550, HiSeq X Ten

ORGANISM(S): Homo sapiens

SUBMITTER: Maddika Subba Reddy 

PROVIDER: E-MTAB-10295 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress