Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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SHP-1 dependent dephosphorylation of Histone H2B acts as a molecular switch to facilitate transcription


ABSTRACT: 1.Comparison of chromatin occupancy of H2BUb and RNA Polymerase II in SHP-1 WT and KO MCF7 cells. Paired end sequencing (2X100 bp) was performed on the Illumina HiSeq X ten. 2.Identification of the SHP-1 binding site in MCF7 cells using ChIP Seq. Paired end sequencing (2X100 bp) was performed on the Illumina Nextseq 2000 platform.

INSTRUMENT(S): NextSeq 550, HiSeq X Ten

ORGANISM(S): Homo sapiens

SUBMITTER: Maddika Subba Reddy 

PROVIDER: E-MTAB-10295 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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