RNAseq of human B-ALL cell lines following RUNX1 or CBFb knock-down

ABSTRACT: Five B-ALL cell lines representing major genetic subtypes were transfected with shRNAs targeting components of the core binding factor (CBF) complex. Five days after transfection, viable, shRNA-expressing cells were sorted and RNA was harvested. RNAseq was performed and knock-down samples compared to non-targeting controls.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Jason Wray 

PROVIDER: E-MTAB-10329 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress