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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Gene expression profiling (RNA-seq) of human iPSCs, iPSC-derived ventralized cells, neurons, and hypothalamic neurons where regions of the genome have been deleted that contain the single nucleotide polymorphisms rs9972768 or rs2650492

ABSTRACT: Three iPSC lines were differentiated into hypothalamic neuron precursors. Line 1 had an enhancer containing rs9972768 deleted, line 2 had an enhancer containing rs2650492 deleted, and the third line was wild-type. Cells were collected for RNA-seq at 4 time points, 1) iPSCs 2) Ventralized cells 3) Neurons of any type and finally 4) Hypothalamic Neurons. There are either 3 or 4 biological clones represented for each line.

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Homo sapiens

SUBMITTER: Noboru Sakabe

PROVIDER: E-MTAB-10464 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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