Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene Expression Profile Analysis of T1 and T2 Breast Cancer Tumors

ABSTRACT: The purpose of this study is to search for molecular signatures characterizing clinical T1 and T2 tumors and to better identify patients of high risk of relapse and/or metastasis. In total 46 samples, 29 T1 and 17 T2 infiltrating ductal carcinomas, were included.

ORGANISM(S): Homo sapiens

SUBMITTER: Torben Lüders

PROVIDER: E-MTAB-1049 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Shared Molecules

Only show the datasets with similarity scores above: 0.5

Threshold

0.5

Similar Datasets

Gene expression data following Cyclin T2 and Cyclin T1 depletion by shRNA in HeLa cells

Project description:We have characterized gene expression changes in HeLa cells following long term depletion of Cyclin T2 or Cyclin T1 using shRNA

2011-08-03 | GSE28339 | GEO

Gene expression data following Cyclin T2 and Cyclin T1 depletion by shRNA in HeLa cells

Project description:We have characterized gene expression changes in HeLa cells following long term depletion of Cyclin T2 or Cyclin T1 using shRNA HeLa cells were transduced with VSV-G pseudotyped lentiviral vectors expressing shRNA against either Cyclin T2 or Cyclin T1. As a control, cells were transduced with shRNA vector with four nucleotides mismatch in the Cyclin T1 mRNA that has been previously shown to have minimal effects on mRNA expression levels. The vectors have a GFP reporter that can be used to estimate transduction efficiency. Five days post-transduction, cells were harvested and total RNA extracted. Transcriptional profiling was carried out on these RNA samples. Two independent biological replicate experiments were carried out in this analysis and the xpression values normalized by GC-RMA and averaged. The following comparisons were made: MM to Cyclin T2 and MM to Cyclin T1.

2011-08-02 | E-GEOD-28339 | biostudies-arrayexpress

Human marginal zone B cell development from early T2 progenitors [MZBTraj]

Project description:B cells emerge from the bone marrow as transitional (TS) B cells that differentiate through T1, T2 and T3 stages to become naïve B cells. We have identified a bifurcation of human B cell maturation from the T1 stage forming IgMhi and IgMlo developmental trajectories. IgMhi T2 cells have higher expression of a4b7 integrin and lower expression of IL4 receptor (IL4R) compared to the IgMlo branch and are selectively recruited into gut-associated lymphoid tissue. IgMhi T2 cells also share transcriptomic features with marginal zone B cells (MZB). Lineage progression from T1 cells to MZB via an IgMhi trajectory is identified by pseudotime analysis of scRNA-sequencing data. Reduced frequency of IgMhi gut homing T2 cells is observed in severe SLE and is associated with reduction of MZB and their putative IgMhi precursors. The collapse of the gut-associated MZB maturational axis in severe SLE affirms its existence in health.

2021-01-31 | GSE163602 | GEO

Human marginal zone B cell development from early T2 progenitors [Pooled]

2021-01-31 | GSE163493 | GEO

Bacteria in manure compost in T1 and T2 periods

Project description:Bacteria in manure compost in T1 and T2 periods Raw sequence reads

| PRJNA980074 | ENA

Transcription profiling of acid exposed H. pylori Two independent exposures (labeled T1 and T2) to pH 5.0. Samples were harvested at 30, 60, 90 and 120 minutes

Project description:Two independent exposures (labeled T1 and T2) to pH 5.0. Samples were harvested at 30, 60, 90 and 120 minutes and used to make cDNA. Arrays are set up such that each time point was hybridized to the individual T=0 starting culture.

2005-10-13 | E-SMDB-1998 | biostudies-arrayexpress

Brassica rapa subsp. oleifera isolate:C1,C2,C3,T1,T2,T3

Project description:Brassica rapa subsp. oleifera isolate:C1,C2,C3,T1,T2,T3 Raw sequence reads

| PRJNA543954 | ENA

Hydrogenophaga sp. T2 strain:T2

Project description:Hydrogenophaga sp. T2 strain:T2 Genome sequencing

| PRJNA1087124 | ENA

Enterobacter sp. T2 strain:T2

Project description:Enterobacter sp. T2 strain:T2 Genome sequencing

| PRJNA604930 | ENA

OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage

Project description:OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage