Unknown,Transcriptomics,Genomics,Proteomics

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Enhancers with tissue-specific activity are enriched in intronic regions

ABSTRACT: We have performed ChIP-seq of H3K27ac and H3K4me3 histone post-translational modifications at three stages during induced neural differentiation (ESCs, neural progenitors and neurons). This data has allowed us to identify candidate enhancer-like signatures in the genome, which we have defined as regions that are enriched in H3K27ac and depleted of H3K4me3.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Beatrice Borsari

PROVIDER: E-MTAB-10595 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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