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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Time-coursed transcriptomics of ATRA-induced granulocytic differentiation

ABSTRACT: Transcriptional profiling of HL-60 cells at 0, 3, 24, and 96 h after ATRA treatment. The differentially expressed genes was meant to be the input data for bioinformatic upstream regulator search

ORGANISM(S): Homo sapiens

SUBMITTER: Svetlana Novikova

PROVIDER: E-MTAB-10606 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptomics of HL60 cell line at 30 min and 1 h after all-trans-retinoic acid (ATRA) treatment

Project description:Transcriptome profiling of HL60 cells at the yearly time points of ATRA treatment (30 min and 1 h) allows to unveil molecular mechanisms of the onset of granulocytic maturation. Transcriptomic techniques are characterized by high sensitivity and allow for detection of low-abundant molecules, such as nuclear transcription factors.

2022-10-01 | E-MTAB-12026 | biostudies-arrayexpress

Nuclear proteomics of induced granulocytic differentiation

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2023-03-11 | PXD035281 | Pride

Transcription profiling of human HL-60 Cells Stimulated by ATRA and DMSO

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Human HL-60 Cells: all-trans retinoic acid (ATRA) vs. ATRA plus arsenic trioxide (ATO)

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Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia [Illumina HumanHT-12 gene expression array]

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2012-03-14 | E-GEOD-34726 | biostudies-arrayexpress

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The Study of ATRA-Induced Differentiation of the HL-60 Cell Line

Project description:Shotgun mass-spectrometric experiment was performed with HL-60 cells induced to differentiation at 0, 3, 24, 48 and 96h after ATRA treatment. Obtained data has been used for label-free quantification by SPIRE platform based on spectral count. Results on proteome profiling were used for up-stream regulator search in geneXplain platform (http://genexplain.com/).

2021-09-07 | PXD006768 | Pride

RNA seq of HL-60 cells in untreated, ATRA (All- trans retinoic acid) and Vitamin D3 treated conditions

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2023-01-25 | E-MTAB-12267 | biostudies-arrayexpress

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