Activation of normal dermal fibroblasts by normal and cancer epithelial cells: clinical samples.

ABSTRACT: We model processes of wound healing and tumor growth, by studying the effects of normal and cancer epithelial cells on normal fibroblasts and their reciprocal effect on normal keratinocytes in vitro. We find strong parallels between the two processes and compare our observations with transcriptional analysis of 24 clinical samples of squamous cell carcinoma. This dataset contains the clinical samples, for tissue culture samples, see E-MTAB-1064. Clinical samples of carcinoma tissues were compared to paired normal mucosae.

ORGANISM(S): Homo sapiens

DISEASE(S): normal

SUBMITTER: Michal Kolar 

PROVIDER: E-MTAB-1065 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress