Transcriptomic analyses of fetal (18.5 dpc) and adult (3 months) mouse testes after in utero BPA and/or ionizing radiations exposure(s)

ABSTRACT: Despite the fact that we are constantly exposed to various environmental compounds, very few studies explore the impact of combined exposure to physical and chemical pollutants on reproductive health. Until now, assessment of pollutants is mostly based on the evaluation of single pollutant or combination of chemicals with common features and modes of action. In this context, numerous studies have demonstrated that steroidogenesis and gametogenesis, the main testicular functions, are well-known to be sensitize by endocrine disruptors (as Bisphenol A) and DNA-damaging agents (as γ-rays) respectively. In this study, we aim to investigate short and long term testicular transcriptionnal alterations of combined fetal exposure to well-known environmental toxicants: γ-rays (RAD) and BPA. To discr

INSTRUMENT(S): GCS3000 7G, fluidic station FS450

ORGANISM(S): Mus musculus

SUBMITTER: Marie-Justine Guerquin 

PROVIDER: E-MTAB-10982 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress