Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Legionella pneumophila wild type vs. rsmYZ

ABSTRACT: regulation of life cycle switch - role of ncRNA

ORGANISM(S): Legionella pneumophila

SUBMITTER: Tobias Sahr 

PROVIDER: E-MTAB-111 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Control of flagellar gene regulation in Legionella pneumophila and its relation to growth phase.

Albert-Weissenberger Christiane C   Sahr Tobias T   Sismeiro Odile O   Hacker Jörg J   Heuner Klaus K   Buchrieser Carmen C  

Journal of bacteriology 20091113 2

The bacterial pathogen Legionella pneumophila responds to environmental changes by differentiation. At least two forms are well described: replicative bacteria are avirulent; in contrast, transmissive bacteria express virulence traits and flagella. Phenotypic analysis, Western blotting, and electron microscopy of mutants of the regulatory genes encoding RpoN, FleQ, FleR, and FliA demonstrated that flagellin expression is strongly repressed and that the mutants are nonflagellated in the transmiss  ...[more]

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