RNA-seq of a VHL-/- human renal cancer cell line 786-0 transfected with 3 vectors

ABSTRACT: The human renal cancer cell line 786-0 was transfected with 3 vectors allowing the doxycycline-inducible expression of 1) the full length wild type sequence of VHL: 786-0 VHL WT, VHL+/+, 2) the R167Q mutant : 786-0 R167Q, VHL mutated, 3) the empty vector : 786-0 EV, VHL-/-. The aim of the study was to examine whether the VHL-R167Q mutation, which is associated with a high risk of developping clear cell renal carcinomas, could impact the plasticity of renal carcinoma cells.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Stéphanie BUART 

PROVIDER: E-MTAB-11168 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress