Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Genomic DNA T b. brucei and T. b. rhodesiense. Data for E-MTAB-3800


ABSTRACT: Genomic DNA T b. brucei and T. b. rhodesiense. These are actually paired reads but the files are unpaired

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Trypanosoma brucei

SUBMITTER: Christine Clayton 

PROVIDER: E-MTAB-11303 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Transcriptomes of newly-isolated Trypanosoma brucei rhodesiense reveal hundreds of mRNAs that are co-regulated with stumpy-form markers.

Mulindwa Julius J   Mercé Clémentine C   Matovu Enock E   Enyaru John J   Clayton Christine C  

BMC genomics 20151229


<h4>Background</h4>During natural Trypanosoma brucei infections, the parasites differentiate spontaneously into a non-dividing "stumpy" form when a certain level of parasitaemia is attained. This form is metabolically adapted for rapid further differentiation into procyclic forms upon uptake by Tsetse flies.<h4>Results</h4>We describe here four central Ugandan isolates of Trypanosoma brucei rhodesiense that have undergone only three rodent passages since isolation from human patients. As expecte  ...[more]

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