RNA-seq data of rs2280381-containing region knock out clone in U-937 cell line

ABSTRACT: rs2280381 is an autoimmune disease susceptible variant, which has been reported to be associated with SLE, RA and SSc. Genetic and epigenomic analysis indicate that the rs2280381-containing region is an enhancer region in monocyte. To test the function and regulated genes of the rs228381-containing region, we deleted the rs2280381 ~120bp sequence in U-937 cells, and performed the RNA-seq to detect the gene expression profiles.

INSTRUMENT(S): HiSeq X Ten

ORGANISM(S): Homo sapiens

SUBMITTER: Guojun Hou 

PROVIDER: E-MTAB-11306 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress