Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Mice lncRNA array for MACF1-knockdown MC3T3-E1 cell line


ABSTRACT: MC3T3-E1 cells with stable knockdown of MACF1 by shRNA. Cells were normally cultured and RNA extracted for lncRNA microarray.

ORGANISM(S): Mus musculus

SUBMITTER: Chong Yin 

PROVIDER: E-MTAB-11426 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

A novel long noncoding RNA AK016739 inhibits osteoblast differentiation and bone formation.

Yin Chong C   Tian Ye Y   Yu Yang Y   Wang Haoyu H   Wu Zhixiang Z   Huang Zizhan Z   Zhang Yan Y   Li Dijie D   Yang Chaofei C   Wang Xue X   Li Yu Y   Qian Airong A  

Journal of cellular physiology 20190117 7


The incidence of postmenopausal osteoporosis research 50% in middle-aged and older women, however, effects of existing therapy are not ideal. Emerging evidence have proved that long noncoding RNAs (lncRNAs) was correlated with multiple physiological and pathology processes including development, carcinogenesis, and osteogenesis. However, reports on lncRNAs regulating bone formation were relatively limited. In this study, we screened osteogenic lncRNAs through mRNA/lncRNA microarray combined with  ...[more]

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