Single-cell sequencing of tissue-resident CD8+ T cells that drive compartmentalized immunopathology in the CNS

ABSTRACT: In chronic inflammatory diseases of the central nervous system (CNS), immune cells persisting behind the blood-brain barrier are supposed to promulgate local tissue destruction. The drivers of such compartmentalized inflammation remain unclear, but tissue-resident memory T cells (TRM) represent a potentially important cellular player in this process

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Alex Yermanos 

PROVIDER: E-MTAB-11511 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress