Biodegradable Nanoparticles Induce cGAS/STING-dependent Reprogramming of Myeloid Cells to Promote Tumor Immunotherapy

ABSTRACT: Spleens were collected from C57BL/6 mice that were treated with (1) saline, (2) a single dose of nanoparticles, (3) 3 doses of nanoparticles administered daily, or (4) 3 doses of nanoparticles administered every 3 days. Single-cell RNA-sequencing was conducted using the 10X Genomics platform and analyzed with Seurat.

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Mus musculus

SUBMITTER: Joseph Podojil 

PROVIDER: E-MTAB-11584 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress