RNA-seq of AD patient-derived induced neurons treated with shikonin

ABSTRACT: We have obtained fibroblast cultures from old adult human control donors and Alzheimer patients. The fibroblasts were reprogrammed into directly induced neurons (iNs) to serve as an adult-like and age-equivalent model for aging and neurodegeneration. iNs were treated for 10 days with 10 µM shikonin or DMSO.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Jerome Mertens 

PROVIDER: E-MTAB-11855 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress