CRISPR screen for the identification of host factors for ZIKA virus infection

ABSTRACT: To search for host factors regulating Zika virus infection, we performed a genome-wide loss-of-function CRISPR/Cas9 screen in haploid human ESCs. The regulators were identified by the quantification of enrichment of their mutant clones within a pooled loss-of-function library upon Zika virus infection.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Atilgan Yilmaz 

PROVIDER: E-MTAB-11945 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress