Cholesterol and TNF-induced transcriptomic changes in Mus musculus aortic smooth muscle cells

ABSTRACT: To map gene regulation downstream of cholesterol overload and NF-kappaB signaling in smooth muscle cells (SMCs), we cultured primary aortic SMCs from wildtype mice with cyclodextrin-complexed cholesterol or the prototypical NF-kappaB activator, tumor necrosis factor (TNF), or both.

INSTRUMENT(S): DNBSEQ-G400

ORGANISM(S): Mus musculus

SUBMITTER:  

PROVIDER: E-MTAB-12069 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): ERP140195E-MTAB-13416

REPOSITORIES: biostudies-arrayexpress