Intracellular hypoxia and heat shock response are essential requirements for amoebic pathogenicity and virulence

ABSTRACT: Amongst several amoebic species that colonize the human gut only Entamoeba histolytica is able to cause tissue damage in the intestine and other organs. Amoebic pathogenicity and virulence are commonly evaluated as the parasiteM-+s ability to produce liver abscesses in hamsters (ALAH). Some molecules involved in several functions that enable E. histolytica to invade and survive in the tissues have been identified and proposed as virulence factors. However, despite the fact that during early tissue invasion E. histolytica has to cope with toxic oxygen concentrations, little attention have received the mechanisms of oxygen resistance and its relationship with pathogenicity and virulence. In this work we compared the ability of virulent E. histolytica, non virulent E. histolytica and non p

ORGANISM(S): Entamoeba histolytica

SUBMITTER: Nora Hernandez 

PROVIDER: E-MTAB-1207 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress