Identification of autoantibodies in colorectal cancer

ABSTRACT: Colorectal cancer remains the leading cause of cancer death worldwide. The 5-year annual survival is less than half of the incidence rate that is predominantly due to late diagnosis of the disease striking the very urgent clinical necessity for biomarkers capable of detecting cancer malignancy at an early onset. During neoplastic transformation, cells undergo several behavioral changes that subsequently result in defects in cell division, immune tolerance, inflammation, and cellular death mechanisms. These processes lead to the development of tumor antigens (TA) that evoke an immune response and subsequent generation of antibodies against self-proteins, called autoantibodies (AAbs). This study aims to identify autoantibody biomarkers in patient’s sera for early screening of the cancer. Hig

INSTRUMENT(S): GenePix 4000B

ORGANISM(S): Homo sapiens

SUBMITTER: Arka Ray 

PROVIDER: E-MTAB-12081 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress