RNA-seq of 7G8 cell bank parasites

ABSTRACT: The parasite Plasmodium falciparum is responsible for severe malaria, which remains a major cause of death, particularly in sub-Saharan Africa. The reference strain NF54 (or its subclone 3D7) is commonly used for controlled human malaria infection (CHMI), but recently strains with a different geographic and genomic background have become available for CHMI, including 7G8, which was subcloned from the Brazilian isolate IMTM22 in 1984 (Burkot TR et al. 1984. Infectivity to mosquitoes of Plasmodium falciparum clones grown in vitro from the same isolate. Trans R Soc Trop Med Hyg 78 (3):339-41. doi: 10.1016/0035-9203(84)90114-7). To provide the first RNA-seq reference dataset for 7G8 ring stage parasites and validate our qPCR primer set targeting all var gene variants above 6 kb encoded in the

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Plasmodium falciparum 7G8

SUBMITTER: Anna Bachmann 

PROVIDER: E-MTAB-12157 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress