Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Human miRNA expression in EBV+ and EBV- PTLD tumor tissue sections


ABSTRACT: Expression of human miRNAs was analyzed in 150 ng of total RNA from nine post-transplant lymphoproliferative disorder (PTLD) patient samples, categorized as Epstein-Barr virus-positive (EBV+ , n = 4) or EBV- (n = 5) PTLD by hybridization on Affymetrix’s GeneChip miR Array 4.0 (Stanford Functional Genomics Facility, Stanford, CA). The Bioconductor ‘oligo’ package was used to perform array background subtraction, quantile normalization, and summarization by median polish. The normalized gene expression dataset was annotated with the ‘pd.mirna.4.0’ annotation library package in R (R Core Team). The expression data was fit to a linear model using the ‘stats’ package in R (R Core Team). Moderated t-statistics and log-odds of differential expression were calculated using the empirical Bayes method. False discovery rate (FDR) tests were performed with the Benjamini-Hochberg procedure for multiple testing correction in R (R Core Team).

ORGANISM(S): Homo sapiens

SUBMITTER: Ayantika Sen 

PROVIDER: E-MTAB-12201 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2014-03-26 | E-MTAB-2453 | biostudies-arrayexpress
2024-05-14 | PXD051912 | Pride
2021-11-03 | PXD024101 | Pride
2007-06-15 | GSE8123 | GEO
2017-12-01 | E-MTAB-5904 | biostudies-arrayexpress
2012-06-23 | GSE38885 | GEO
| PRJNA794935 | ENA
2008-06-16 | E-GEOD-8123 | biostudies-arrayexpress
2012-06-22 | E-GEOD-38885 | biostudies-arrayexpress
2010-07-30 | E-GEOD-18018 | biostudies-arrayexpress