ATACseq of mouse hematopoietic stem cells after 4 hours of LPS/PBS treatment in vivo

ABSTRACT: To understand whether hematopoietic stem cells (HSCs) take part in emergency granulopoiesis, WT C57BL6 mice were treated intraperitoneally with 35 ug of lipopolysacharide (LPS) to induce emergency granulopoiesis, or PBS control. Mice were sacrificed 4 hours after the treatment and HSCs (Lin-c-Kit+Sca-1+CD48-CD150+) were sorted and subjected to bulk ATACseq.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Mus musculus

SUBMITTER: Jan Kubovčiak 

PROVIDER: E-MTAB-12310 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress