Bulk RNA-seq datasets of co-injected naked mole rat and human fibroblasts to NSG mice 2022

ABSTRACT: To study the tumour-suppressive capabilities of naked mole-rat fibroblasts we subcutaneously co-injected the fibroblasts and human squamous carcinoma cells into the flanks of NSG mice, which lack mature T cells. As controls, we (1) performed the co-injection experiment with mouse fibroblasts, and (2) performed experiments in which we injected human squamous carcinoma cells without mouse or naked mole-rat fibroblasts. To determine how the co-injections with mouse or naked mole-rat fibroblasts affected tumour growth in vivo, we then transcriptionally profiled the human skin tumours.

INSTRUMENT(S): NextSeq 550

ORGANISM(S): Homo sapiens

SUBMITTER: Pablo Baeza Centurion 

PROVIDER: E-MTAB-12455 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress