Single-cell RNA-Sequencing of pancreatic and PDAC stromal cells
Ontology highlight
ABSTRACT: Most cancers including pancreatic ductal adenocarcinoma (PDAC) are infiltrated by PNS neurons participating in their complex tumor microenvironment. However, their cell bodies and nuclei are located in the para- and pre-vertebral PNS ganglia located far from the tumor mass itself. Thus, molecular information on healthy organ- vs. cancer-infiltrating neurons is currently lacking in any sequencing dataset of healthy or tumor tissue. Here, we specifically isolate fibroblasts, immune, endothelial and PDAC cells and subject them to single-cell RNA-Sequencing using the 10x genomics platform.
INSTRUMENT(S): NextSeq 550
ORGANISM(S): Mus musculus
SUBMITTER:
PROVIDER: E-MTAB-12906 | biostudies-arrayexpress |
SECONDARY ACCESSION(S): ERP168589
REPOSITORIES: biostudies-arrayexpress
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