Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Single-cell RNA-Sequencing of pancreatic and PDAC stromal cells


ABSTRACT: Most cancers including pancreatic ductal adenocarcinoma (PDAC) are infiltrated by PNS neurons participating in their complex tumor microenvironment. However, their cell bodies and nuclei are located in the para- and pre-vertebral PNS ganglia located far from the tumor mass itself. Thus, molecular information on healthy organ- vs. cancer-infiltrating neurons is currently lacking in any sequencing dataset of healthy or tumor tissue. Here, we specifically isolate fibroblasts, immune, endothelial and PDAC cells and subject them to single-cell RNA-Sequencing using the 10x genomics platform.

INSTRUMENT(S): NextSeq 550

ORGANISM(S): Mus musculus

SUBMITTER:  

PROVIDER: E-MTAB-12906 | biostudies-arrayexpress |

SECONDARY ACCESSION(S): ERP168589

REPOSITORIES: biostudies-arrayexpress

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