DNA-Protein Crosslink sequencing (DPC-seq) in RPE-1 cells treated with formaldehyde

ABSTRACT: Covalent DNA-protein crosslinks (DPC) are toxic DNA lesions that require repair by global-genome and replication-coupled pathways. How cells respond when RNA polymerases stall at DPCs during transcription is unknown. DPC-seq is new method for the genome-wide mapping of covalent DNA-protein adducts.

INSTRUMENT(S): Illumina HiSeq 1500, Illumina NovaSeq 6000, NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Aldo Bader 

PROVIDER: E-MTAB-12912 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress