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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Human periodontal ligament fibroblasts (PdLFs) were treated with L-lactic acid, a metabolite from periapical granulomas, in comparison to the untreated and positive controls

ABSTRACT: Human PdLFs (iCell Bioscience, China) were treated with 1µM, 10µM, and 100µM L-lactic acid (Sigma-Aldrich, Germany). Phorbol 12-myristate 13-acetate (PMA) (ab120297, Abcam, UK) at 1µM was used as an inflammatory inducer, a positive control for the expression and synthesis of collagen and MMP-1. Untreated PdLFs were regarded as control. PdLFs were incubated at 37°C and 5% CO2 for 2 days and 6 days.

ORGANISM(S): Homo sapiens

SUBMITTER: Alaa Abed

PROVIDER: E-MTAB-12932 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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