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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcriptome profiling by RNA-seq of fibroblast isolated from a brain pathological tissue

ABSTRACT: In this study, we address the difference in adult fibroblasts developmentally originating from different germ layers. Closer, we focussed on HOX gene expression and the potential influence of physiological and pathological conditions in postnatal life. Here we specifically focused on fibroblasts from epileptogenic focus, glioblastoma, soft tissue between galea aponeurotica and periost, and metastases to the brain, at the scale of whole genome expression. Fibroblasts were prepared using the fibroblast-specific kit (Fibroblast MicroBeads, Miltenyi, Bergisch Gladbach, Germany) according to the manufacturer´s instructions.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Homo sapiens

SUBMITTER: Lucie Pfeiferova

PROVIDER: E-MTAB-13242 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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