RNA-Seq from Primate iPSC derived Astrocytes (iAstrocytes)
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ABSTRACT: RNA-Seq experiment to detect transcriptional differences in iPSC derived astrocytes between 3 primate species, humans, chimpanzees and macaques. The goal of the experiment is to characterise genome-wide evolutionary changes in transcriptional and regulatory systems across the primate lineage in astrocytes
Project description:ATAC-seq experiments were performed to map the open chromatin regions of human, chimpanzee and macaque iAstrocytes. This experiment allowed to compare evolutionary changes according to chromatin activity.
Project description:H3K4me3 ChIP-Seq experiment was performed to map and compare potential evolutionary changes in active promoters of human, chimpanzee and macaque iAstrocytes.
Project description:H3K27ac ChIP-Seq experiment was performed to map and compare potential evolutionary changes in active promoters and enhancer elements of human, chimpanzee and macaque iAstrocytes.
Project description:CTCF ChIP-Seq experiment was performed to map and compare potential evolutionary changes of CTCF binding, chimpanzee and macaque iAstrocytes.