Identification of potential miR-31 target-genes in Ewing Sarcoma

ABSTRACT: We identified miR-31 as strongest downregulated miRNA in the bone tumor Ewing sarcoma. To identify miR-31 targets in ES genome-wide gene expression profiles of TC71 cells transfected with miR-31 mimics or negative control (Life Technologies) generated in three independent experiments (a, b, c). Total RNA was isolated from cells after 72 h incubation in serum-reduced medium (1% FCS) and three transfections. Fifteen upregulated and 14 downregulated genes were detected with a 2 fold change cut-off (FDR <0.05).

ORGANISM(S): Homo sapiens

SUBMITTER: Bianca Karnuth 

PROVIDER: E-MTAB-1334 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress