DMG H3-K27M MAPK-altered methylation data

ABSTRACT: Diffuse midline gliomas (DMG) are aggressive tumors with a poor prognosis. In this study, a technique called t-SNE analysis was used to cluster tumors based on their methylation profiles. DMG subtype with a co-occurrence of H3.3K27M and BRAF or FGFR1 mutations have been identified. This subtype has a more favorable prognosis, with a median overall survival of 3 years.

ORGANISM(S): Homo sapiens

SUBMITTER:  

PROVIDER: E-MTAB-13471 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress