RNA-seq of Pseudomonas Aeruginosa grown under sublethal doses of UVA or in the dark up to early logarithmic phase

ABSTRACT: Ultraviolet A (UVA) radiation is the major fraction of UV radiation reaching the Earth’s surface; its harmful effects on microorganisms obey mainly to oxidative damage, with the consequent loss of bacterial viability. In this work, the global transcriptional response of Pseudomonas aeruginosa exposed to UVA was analyzed. P. aeruginosa is an opportunistic human pathogen, also present in terrestrial and aquatic environments; its high ubiquity and versatily obeys to a complex regulatory network wich allows it to adapt to stressful conditions. To conduct this study, the PAO1 strain was grown in under sublethal doses of UVA or in the dark up to early logarithmic phase, and total RNA was obtained and sequenced by the RNA-seq technique. The analysis of the results, taking as significant a factor

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Pseudomonas aeruginosa

SUBMITTER: Magdalena Pezzoni 

PROVIDER: E-MTAB-13681 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress