Transcriptomic profiling of adrenal gland of pigs carrying different genotypes at the gain-of-function mutation of glucocorticoid receptor

ABSTRACT: We have reported the GRAla610Val substitution mutation in pigs (Murani et.al., 2012; DOI: 10.1371/journal.pone.0045518). This experiment aims to investigate the adrenal gland transcriptomic profile of pigs with different genotypes at the GRAla610Val under unchallenged/resting environmental condition of both male and female pigs. The transcriptome signatures and differentially expressed genes associated with the genotypes may provide insights into mechanisms modulating glucocorticoid sensitivity and better understanding of phenotypic consequences as well as sex-specific effects of the GRAla610Val substitution.

INSTRUMENT(S): Illumina HiSeq 2500

ORGANISM(S): Sus scrofa

SUBMITTER: Nares Trakooljul 

PROVIDER: E-MTAB-13760 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress