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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Effects of SFPQ-TFE3 fusion in kidney tubuloids

ABSTRACT: The goal of this study was to analyse the effects of the SFPQ-TFE3 fusion by transforming kidney tubuloids with the construct. Samples without the construct (luciferase only) and overexpressing the partner only (TFE3) were also used as controls. Furthermore, transformed organoids were also transferred into mice PDX models to check their tumorigenic potential; tumors derived from the organoids were subsequently used for sequencing.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Terezinha Maria de Souza

PROVIDER: E-MTAB-13901 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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