TRAP-seq of astrocytes in the APP NL-F knock-in model of ß-amyloidopathy

ABSTRACT: While mouse models of ß-amyloidopathy recapitulate aspects of Alzheimer's disease pathology, including plaque formation and synapse loss, most progress at a speed such that outcomes are studied in the mature mouse, rather than the aged mouse. Here we investigated Aß-dependent changes to astrocytes in a knock-in model of ß-amyloidopathy (APP NL-F) that is known to progress more slowly.

INSTRUMENT(S): NextSeq 500

ORGANISM(S): Mus musculus

SUBMITTER: Owen Robert Dando 

PROVIDER: E-MTAB-13936 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress