Effects of the Sox17mut5 mutation on SOX17 function in mouse embryonic gallbladder development

ABSTRACT: To determine the role of specific cis-regulatory elements within the Sox17 endoderm-preferential TSS2 promoter, we generated Sox17mut5 mutant animals and surveyed how this mutation altered Sox17 expression. Gallbladders were isolated from P21 Sox17mut5/mut5 and Sox17+/+ (n = 4 of each genotype), RNA isolated, and bulk RNA-Seq performed.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Jean-Philippe Cartailler 

PROVIDER: E-MTAB-13978 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress